Cooling agent WS-12 (CAS 68489-09-8), chemically N-(4-cyanomethylphenyl)-p-menthane-3-carboxamide, is the long-distance runner of the WS cooling agent family. Its cooling builds gradually and then lasts dramatically longer than menthol or WS-3 — which has made WS-12 the go-to ingredient for cosmetics, lip care, skin care and premium confectionery where a lingering, comfortable coolness is the goal.
What Is Cooling Agent WS-12 (68489-09-8)?
WS-12 was developed to extend cooling duration far beyond what first-generation agents can achieve. It is a low-odor, white crystalline powder that works on the TRPM8 cold receptors like its relatives, but its molecular structure slows the release of the cooling sensation. The result is a gentle onset followed by a long, stable cooling tail — ideal for leave-on cosmetics and slow-consumed products such as lollipops and chewing gum.
Key Properties of Cooling Agent WS-12
| Property | Specification |
|---|---|
| Product Name | Cooling Agent WS-12 |
| CAS No. | 68489-09-8 |
| Chemical Name | N-(4-Cyanomethylphenyl)-p-menthane-3-carboxamide |
| Appearance | White crystalline powder |
| Odor | Very low odor |
| Purity | ≥99% (typical, COA available on request) |
| Solubility | Freely soluble in ethanol and propylene glycol; low water solubility |
Cooling Profile & Sensory Characteristics
WS-12 has a characteristic slow onset: the cooling effect appears gradually over the first minute and then persists for a remarkably long time. The sensation is soft and comfortable rather than aggressive, with no bitterness issues at normal use levels. Because of this gentle curve, WS-12 is frequently blended with fast-onset agents like WS-10 or WS-3 to create a complete “instant + lasting” cooling experience.
Applications of Cooling Agent WS-12
WS-12 excels in applications where cooling must last:
Cosmetics & Skin Care
Face creams, eye gels, lotions, after-sun and aftershave products. WS-12 provides a calm, long-lasting refreshing effect that consumers perceive as premium quality.
Lip Care
Lip balms, lip gloss and lip serums — one of the classic uses of WS-12, giving lips a pleasant cool feel that lasts.
Premium Confectionery
Lollipops, slow-dissolve candy and chewing gum where the cooling should accompany the product from start to finish.
E-Liquids
Used together with faster agents to extend the cooling tail in premium e-liquid formulations.
Recommended Use & Dosage
WS-12 is effective at low ppm levels; typical dosages depend strongly on the matrix and the desired duration. As a rule of thumb, use less WS-12 than you would WS-3 — its longevity more than compensates. Ask ZHII for detailed starting formulations.
Packaging & Storage
Cooling Agent WS-12 is typically supplied in 1 kg aluminum foil bags and 25 kg fibre drums; custom packing is available on request. Store in a cool, dry place away from direct sunlight, tightly sealed to protect the powder from moisture. When stored properly, the product remains stable for at least 24 months from the production date.
Why Source Cooling Agent WS-12 from ZHII?
- Factory-direct supply — we manufacture and export cooling agents from Xi’an, China, with competitive pricing and stable long-term stock.
- Certified quality — ISO9001 and ISO14001 certified production; KOSHER and HALAL certified products; a Certificate of Analysis accompanies every batch.
- Global experience — customers in more than 50 countries across the EU, the Americas and Asia trust ZHII as their cooling agent supplier.
- Flexible quantities — from free evaluation samples and small trial packs to full container loads.
- Technical support — our team provides formulation guidance, regulatory documents and application advice.
Frequently Asked Questions
Why is WS-12 the favorite for cosmetics?
Because it is low-odor, non-irritating at use levels, and its slow, long-lasting cooling feels gentle and premium on the skin — exactly what leave-on cosmetic products need.
How long does the cooling of WS-12 last?
Depending on dosage and matrix, the cooling effect of WS-12 can persist significantly longer than menthol or WS-3, often for many minutes — it is the longest-lasting agent in the WS family.
Can I buy WS-12 in small quantities for testing?
Yes. ZHII provides free evaluation samples of WS-12, and commercial quantities start from 1 kg packs with fast worldwide delivery.
Get a Free Sample of Cooling Agent WS-12
Looking for a reliable Cooling Agent WS-12 manufacturer and supplier? ZHII offers high-purity Cooling Agent WS-12 (68489-09-8) with fast worldwide delivery and free samples. Visit our cooling agent powder page to explore the full WS series, or contact us today by email at sxzhiyi@126.com or WhatsApp +86 151 0299 2009 for a quotation within 24 hours.
