Menthyl PCA (CAS 64519-44-4), the L-menthyl ester of pyrrolidone carboxylic acid (PCA), is a unique dual-function cosmetic active: a gentle cooling agent and a natural moisturizing factor. Skin enzymes slowly hydrolyze the ester, gradually releasing L-menthol — which activates the skin’s TRPM8 cold receptors — together with PCA, a key component of the skin’s natural moisturizing factor. The result is a soothing, cooling and hydrating effect lasting 8 hours or more, with zero irritation.
Menthyl PCA Specifications
| Parameter | Specification |
|---|---|
| Product Name | Menthyl PCA (INCI: Menthyl PCA) |
| CAS No. | 64519-44-4 |
| EINECS No. | 264-935-8 |
| Chemical Name | L-Pyroglutamic acid menthyl ester |
| Appearance | Colorless to pale yellow viscous liquid |
| Odor | Tasteless to faint cool, slightly woody-herbal |
| Purity | ≥96% (COA available on request) |
| Molecular Formula | C15H25NO3 (MW 267.36) |
| Solubility | Soluble in alcohols and oils; partially soluble in water |
| Packaging | 1 kg bottle / 25 kg drum (customizable) |
| Shelf Life | 24 months from production date (proper storage) |
Cooling Profile & Functional Benefits
Menthyl PCA stands apart from physical cooling agents through its slow-release mechanism. Instead of an immediate menthol shock, it delivers a progressive, natural cooling sensation that continues for more than 8 hours as skin enzymes hydrolyze the ester. Meanwhile the released PCA replenishes the skin’s natural moisturizing factor, providing genuine hydration rather than mere sensory cooling. It is mild, non-irritating and suitable for sensitive skin — which is why it is a favorite in after-sun, deodorant, foot care and “all-day freshness” products. It also shows good synergy with fragrance systems and can enhance the cooling feel of mosquito-repellent formulations.
Applications of Menthyl PCA
Skin Care
Moisturizers, gels, after-sun products — cooling and hydration in one ingredient.
Body & Foot Care
Deodorants, foot creams, tired-leg gels — all-day soothing freshness.
Hair Care
Shampoos, conditioners, scalp treatments — refreshing, calming sensation.
Shaving & Fragrance
Aftershaves, shaving gels, colognes — gentle cool comfort, no stinging.
Recommended Use & Dosage
Typical use levels range from 0.1% to 2.0% depending on the product category (e.g. up to 0.8% in body lotions, up to 1.9% in hand creams). Add at temperatures below 40°C to preserve performance; for aqueous systems, pre-solubilize in alcohol, butylene glycol or oils first. Contact our technical team for formulation support.
Packaging & Storage
Menthyl PCA is supplied in 1 kg bottles and 25 kg drums; custom packing is available on request. Store in a cool, dry place away from direct sunlight, tightly sealed. When stored properly, the product remains stable for at least 24 months from the production date.
Why Source Menthyl PCA from ZHII?
- Factory-direct supply — we manufacture and export from Xi’an, China, with competitive pricing and stable long-term stock.
- Certified quality — ISO9001 and ISO14001 certified; KOSHER and HALAL certified; COA with every batch.
- Global experience — customers in 50+ countries across the EU, Americas and Asia.
- Flexible quantities — from free samples and 1 kg trial packs to full container loads.
- Technical support — formulation guidance, regulatory documents and application advice.
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